Liverpool Football Club
Premier League All Time Defeats v Southampton - 10
| Date | Opponents | Home/Away | W/D/L |
Score |
| 13/02/1993 | Southampton | Away | L | 1-2 |
| 14/02/1994 | Southampton | Away | L | 2-4 |
| 07/02/1998 | Southampton | Home | L | 2-3 |
| 09/01/2002 | Southampton | Away | L | 0-2 |
| 13/12/2003 | Southampton | Home | L | 1-2 |
| 14/03/2004 | Southampton | Away | L | 0-2 |
| 22/01/2005 | Southampton | Away | L | 0-2 |
| 16/03/2013 | Southampton | Away | L | 1-3 |
| 21/09/2013 | Southampton | Home | L | 0-1 |
| 20/03/2016 | Southampton | Away | L | 2-3 |
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