| Date | Opponent | H/A | Comp | Score | Result | TV Station |
| August 2021 | ||||||
| 14.08.2021 | Norwich City | A | EPL | 3:0 | Won | Sky Sports |
| 21.08.2021 | Burnley | H | EPL | 2:0 | Won | BT Sports |
| 28.08.2021 | Chelsea | H | EPL | 1:1 | Draw | Sky Sports |
| September 2021 | ||||||
| 12.09.2021 | Leeds United | A | EPL | 3:0 | Won | Sky Sports |
| 25.09.2021 | Brentford | A | EPL | 3:3 | Draw | Sky Sports |
| October 2021 | ||||||
| 03.10.2021 | Manchester City | H | EPL | 2:2 | Draw | Sky Sports |
| 16.10.2021 | Watford | A | EPL | 5:0 | Won | BT Sports |
| 24.10.2021 | Manchester United | A | EPL | 5:0 | Won | Sky Sports |
| November 2021 | ||||||
| 07.11.2021 | West Ham United | A | EPL | 2:3 | Lost | Sky Sports |
| 20.11.2021 | Arsenal | H | EPL | 4:0 | Won | Sky Sports |
| December 2021 | ||||||
| 01.12.2021 | Everton | A | EPL | 4:1 | Won | Amazon Prime |
| 16.12.2021 | Newcastle United | H | EPL | 3:1 | Won | BT Sports |
| 19.12.2021 | Tottenham Hotspur | A | EPL | 2:2 | Draw | Sky Sports |
| 28.12.2021 | Leicester City | A | EPL | 0:1 | Lost | Sky Sports |
| January 2022 | ||||||
| 02.01.2022 | Chelsea | A | EPL | 2:2 | Draw | Sky Sports |
| 23.01.2022 | Crystal Palace | A | EPL | 3:1 | Won | Sky Sports |
| February 2022 | ||||||
| 10.02.2022 | Leicester City | H | EPL | 2:0 | Won | BT Sports |
| March 2022 | ||||||
| 05.03.2022 | West Ham United | H | EPL | 1:0 | Won | Sky Sports |
| 12.03.2022 | Brighton | A | EPL | 2:0 | Won | BT Sports |
| 16.03.2022 | Arsenal | A | EPL | 2:0 | Won | Sky Sports |
| April 2022 | ||||||
| 02.04.2022 | Watford | H | EPL | 2:0 | Won | BT Sports |
| 10.04.2022 | Manchester City | A | EPL | 2:2 | Draw | Sky Sports |
| 19.04.2022 | Manchester United | H | EPL | 4:0 | Won | Sky Sports |
| 24.04.2022 | Everton | H | EPL | 2:0 | Won | Sky Sports |
| 30.04.2022 | Newcastle United | A | EPL | 1:0 | Won | BT Sports |
| May 2022 | ||||||
| 07.05.2022 | Tottenham Hotspur | H | EPL | 1:1 | Draw | BT Sports |
| 10.05.2022 | Aston Villa | A | EPL | 2:1 | Won | Sky Sports |
| 17.05.2022 | Southampton | A | EPL | 2:1 | Won | Sky Sports |
| 23.05.2022 | Wolverhampton Wanderers | H | EPL | 3:1 | Won | Sky Sports |